Additional volumetric modulated arc therapy to vertebral metastases abutting the previously irradiated site
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Abstract
Introduction: Lung cancer frequently causes metastases to the spine, especially to the thoracic vertebrae, which sometimes compress the spinal cord and induce irreversible palsy. Many patients suffering from metastatic spinal tumors need to undergo repetitive radiotherapy. In such situations, intensity-modulated radiotherapy including volumetric modulated arc therapy can reduce the dose delivered to the spinal cord at the junction.
Case Report: The authors describe a case of thoracic vertebral metastases from lung cancer treated with two courses of radiotherapy. In the second course, volumetric modulated arc therapy was adopted and a columnar-shaped planning target volume with a concave portion was configured.
Conclusion: The authors propose an approach aimed at realizing both junctional safety and the conformality of the spinal column, which may be an option for repetitive irradiation to heterochronic spinal metastases.
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Copyright (c) 2014 Sakashita B, et al.
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Rief H, Muley T, Bruckner T, Welzel T, Rieken S, et al. (2014) Survival and prognostic factors in non-small cell lung cancer patients with spinal bone metastases. Strahlenther Onkol 190: 59-63.
Kaasa S, Brenne E, Lund JA, Fayers P, Falkmer U, et al. (2006) Prospective randomised multicenter trial on single fraction radiotherapy (8 Gy×1) versus multiple fractions (3 Gy×10) in the treatment of painful bone metastases. Radiother Oncol 79: 278-284.
Emami B, Lyman J, Brown A, Coia L, Goitein M, et al. (1991) Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21: 190-122.
Kirkpatrick JP, van der Kogel AJ, Schultheiss TE (2010) Radiation dose-volume effects in the spinal cord. Int J Radiat Oncol Biol Phys 76: S42-S49.
Navarria P, Mancosu P, Alongi F, Pentimali S, Tozzi A, et al. (2012) Vertebral metastases reirradiation with volumetric-modulated arc radiotherapy. Radiother Oncol 102: 416-420.
Ryu S, Fang Yin F, Rock J, Zhu J, Chu A, et al. (2003) Image-guided and intensity-modulated radiosurgery for patients with spinal metastasis. Cancer 97: 2013-2018.
Milker-Zabel S, Zabel A, Thilmann C, Schlegel W, Wannenmacher M, et al. (2003) Clinical results of retreatment of vertebral bone metastases by stereotactic conformal radiotherapy and intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 55: 162-167.
Sutcliffe P, Connock M, Shyangdan D, Court R, Kandala NB, et al. (2013) A systematic review of evidence on malignant spinal metastases: natural history and technologies for identifying patients at high risk of vertebral fracture and spinal cord compression. Health Technol Assess 17: 1-274.