A case with rare manifestation of Cronkhite-Canada Syndrome with remission after treatment and literature review
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Abstract
Cronkhite-Canada syndrome is a rare disorder which is sporadic in nature, its pathology and cause is not fully understood, usually characterized by the presence of polyps in the stomach and large intestine and less frequently in the oesophagus with associated, the aim of this report is to discuss the pathogenesis of this syndrome and possible treatment options, in this case there was a non-conventional approach applied to this with a good prognosis, the disease itself is usually present among the Japanese population with a male to female ratio 2:1 but was of irrelevance as our patient was Indian, this report will also shed some light on the use of herbal medicine and its application in the treatment of this disease along with conventional medicine.
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Bandyopadhyay D, Hajra A, Ganesan V, Kar SS, Bhar D, Layek M, et al. (2016) Cronkhite- Canada Syndrome; a Case Report and Review of the Literature. Case Rep Med 4210397. Link: https://goo.gl/vk3fqr
Seth S, Boardman LA. Cronkhite-Canada Syndrome an Acquired Condition of Gastrointestinal Polyposis and Dermatologic Abnormalities. Gastroenterol Hepatol (N Y) 8: 201–203. Link: https://goo.gl/pNnUa6
Berzin TM, Greenberger NJ, Levy BD, Loscalzo J (2012) Worth a second look. New Eng J Med 366: 463–468. Link: https://goo.gl/jvM19v
Rubio CA, Bjork J (2016) Cronkhite-Canada syndrome - A Case report. Anticancer Res 36: 4215–4217. Link: https://goo.gl/HDKQDg
Daniel ES, Ludwig SL, Lewin KJ, Ruprecht RM, Rajacich GM, Schwabe AD (1992) The Cronkhite-Canada Syndrome. An analysis of clinical and pathologic features and therapy in 55 patients. Medicine (Baltimore) 61: 293-309. Link: https://goo.gl/YhC56E
Kao KT, Patel JK, Pampati V (2009) Cronkhite-Canada syndrome: a case report and review of literature. Gastroenterology Research and Practice 2009: 4. Link: https://goo.gl/FRmmPz
Cronkhite LW, Canada WJ (1955) Generalised gastrointestinal polyposis—an unusual syndrome of polyposis, pigmentation, alopecia and onychotrophia. The New England Journal of Medicine 252: 1011–1015. Link: https://goo.gl/WMiT8C
Ward EM, Wolfsen HC (2002) Review article: the non-inherited gastrointestinal polyposis syndromes. Alimentary Pharmacology and Therapeutics 16: 333–342. Link: https://goo.gl/k92D2o
Riegert-Johnson DL, Osborn N, Smyrk T, Boardman LA (2007) Cronkhite-Canada syndrome hamartomatous polyps are infiltrated with IgG4 plasma cells. Digestion 75: 96–97. Link: https://goo.gl/k43GCm
Calva D, Howe JR (2008) Hamartomatous polyposis syndromes. Surgical Clinics of North America 88: 779–817. Link: https://goo.gl/3knvp8
Chakrabarti S (2015) Cronkhite-Canada Syndrome (CCS)—A Rare Case Report. J Clin Diagn Res 9: OD08–OD09. Link: https://goo.gl/zeh7fr
Seshadri D, Karagiorgos N, Hyser MJ (2012) A case of cronkhite-Canada syndrome and a review of gastrointestinal polyposis syndromes. Gastroenterol Hepatol (N Y) 8: 197-201. Link: https://goo.gl/w29efS
Bettington M, Brown IS, Kumarasinghe MP, de Boer B, Bettington A, et al. (2014) The Challenging Diagnosis of Cronkhite-Canada Syndrome in the Upper Gastrointestinal Tract. Am J Surg Pathol 38: 215–223. Link: https://goo.gl/sCc4Z1
She Q, Jiang JX, Si XM, Tian XY, Shi RH, et al. (2013) A Severe Course of Cronkhite-Canada Syndrome and the Review of Clinical Features and Therapy in 49 Chinese Patients. Turk J Gastroenterol 24: 277–285. Link: https://goo.gl/xw5i7T
Watanabe C, Komoto S, Tomita K, Hokari R, Tanaka M, et al. (2016) Endoscopic and Clinical Evaluation of Treatment and Prognosis of Cronkhite–Canada Syndrome: a Japanese Nationwide Survey. J Gastroenterol 51: 327–336. Link: https://goo.gl/BES3sn
Ward EM, Wolfsen HC (2003) Pharmacological Management of Cronkhite–Canada Syndrome. Expert Opin Pharmacother 4: 385–389. Link: https://goo.gl/sPumRV
Charoensiddhi S; Anprung P (2010) Characterization Of Bael Fruit (Aegle Marmelos [L.] Correa) Hydrolysate As Affected By Enzyme Treatment. Journal of Food Biochemistry 34: 1249–1267. Link: https://goo.gl/qZKYyf
Maity P1, Hansda D, Bandyopadhyay U, Mishra DK (2009) Biological Activities of Crude Extracts and Chemical Constituents of Bael, Aegle Marmelos (L.) Corr. Indian J Exp Biol 47: 849–861. Link: https://goo.gl/qK5yDL
Ghosh S, Playford RJ (2003) Bioactive Natural Compounds for the Treatment of Gastrointestinal Disorders. Clin Sci (Lond) 104: 547–556. Link: https://goo.gl/bLXjnL
Mazumder R, Bhattacharya S, Mazumder A, Pattnaik AK, Tiwary PM, et al. (2006) Antidiarrhoeal Evaluation Of Aegle Marmelos (Correa) Linn. Root Extract. Phytother Res 20: 82–84. Link: https://goo.gl/uz4Ucw
Kaur P, Walia A, Kumar S, Kaur S (2009) Antigenotoxic activity of polyphenolic rich extracts from Aegle marmelos (L.) Correa in human blood lymphocytes and E. coli. Nat Prod Rec 3: 68–75. Link: https://goo.gl/vUXUfp
Baliga MS, Thilakchand KR, Rai MP, Rao S, Venkatesh P (2013) Aegle Marmelos (L.) Correa (Bael) and Its Phytochemicals in the Treatment and Prevention of Cancer. Integr Cancer Ther 12: 187–196. Link: https://goo.gl/nqDCLR
Zong Y, Zhao H, Yu L, Ji M, Wu Y, et al. (2017) Case Report—Malignant Transformation in Cronkhite–Canada Syndrome Polyp. Medicine (Baltimore) 96: e6051. Link: https://goo.gl/JScGK4
Ezzat SM, Ezzat MI, Okba MM, Menze ET, Abdel-Naim AB (2018) The Hidden Mechanism beyond Ginger ( Zingiber Officinale Rosc.) Potent in Vivo and in Vitro Anti-Inflammatory Activity. J Ethnopharmacol 214: 113–123. Link: https://goo.gl/u4nt1R
Haniadka R, Saldanha E, Sunita V, Palatty PL, Fayad R, et al. (2013) A Review of the Gastroprotective Effects of Ginger (Zingiber Officinale Roscoe). Food Funct 6: 845–855. Link: https://goo.gl/LKze6s
Tiwari P, Mishra BN, Sangwan NS (2014) Phytochemical and Pharmacological Properties Of Gymnema Sylvestre: An Important Medicinal Plant. BioMed Research International, 2014: 1–18. Link: https://goo.gl/mVhhRF
Jain KS, Kathiravan MK, Somani RS, Shishoo CJ (2007) The Biology and Chemistry of Hyperlipidemia. Bioorg Med Chem 15: 4674–4699. Link: https://goo.gl/e1zqqJ
Jamadagni PS, Pawar SD, Jamadagni SB, Chougule S, Gaidhani SN, et al. (2017) Review of Holarrhena Antidysenterica (L.) Wall. Ex A. DC.: Pharmacognostic, Pharmacological, and Toxicological Perspective. Pharmacogn Rev 11: 141–144. Link: https://goo.gl/YEGRkH
Pal A, Sharma PP, Mukherjee PK (2009) A clinical study of Kutaja (Holarrhena antidysenterica wall) on Shonitarsha. AYU 30: 369–372. Link: https://goo.gl/JYnpJD
Wang YC1, Huang TL (2005) Anti-Helicobacter Pylori activity Of Plumbago Zeylanica L. FEMS Immunol Med Microbiol 43: 407–412. Link: https://goo.gl/yGkM2m
Iyengar MA, Pendse GS (1996) Plumbago Zeylanica L. (Chitrak) A Gastrointestinal Flora Normaliser. Planta Med 14: 337–351. Link: https://goo.gl/TbFd19
Yadav V, Chatterjee SS, Majeed M, Kumar V (2015) Long Lasting Preventive Effects of Piperlongumine and a Piper Longum Extract against Stress Triggered Pathologies in Mice. J Intercult Ethnopharmacol 4: 277–283. Link: https://goo.gl/QG2xVS
Sharma AL, Bhot MA, Chandra N (2014) Gastroprotective Effect of Aqueous Extract and Mucilage from Bryophyllum Pinnatum (Lam.) Kurz. Ancient Science of Life 33: 252–258. Link: https://goo.gl/YKNcV6
Ranasinghe P, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, et al. (2013) Medicinal Properties of ‘True’ Cinnamon (Cinnamomum Zeylanicum): a Systematic Review. BMC Complement Altern Med 13: 275. Link: https://goo.gl/YiRXp2